January 14, 2026 7:56 pm

Author: Share IBD Movement

New Hope for Severe Crohn’s: Breakthrough Drug Targets Scarring

Agomab Therapeutics has launched a groundbreaking clinical trial for ontunisertib, a drug specifically targeting fibrostenosing Crohn’s disease—the severe, scarring form that has limited treatment options. This represents the first targeted therapy designed to address the root cause of intestinal scarring rather than just managing symptoms.

The FMT Study That Didn’t Work: What It Teaches Us About Crohn’s

A recent study tested fecal microbiota transplantation (FMT) for Crohn’s disease with disappointing results—but what can we learn from this setback? While FMT didn’t improve remission rates in 8 weeks, the research offers valuable insights for future treatments and reminds us that progress in IBD research often comes through understanding what doesn’t work.

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